Molecular mechanisms of physiological change under acute total dissolved gas supersaturation stress in yellow catfish (Pelteobagrus fulvidraco)
文献类型： 外文期刊
作者： Chen, Yeyu 1 ; Wu, Xiaoyun 1 ; Lai, Jiansheng 1 ; Yan, Boqin 1 ; Gong, Quan 1 ;
作者机构： 1.Sichuan Acad Agr Sci, Fishery Inst, Chengdu 611730, Peoples R China
关键词： Pelteobagrus fulvidraco; Total dissolved gas; Gas bubble disease; Heat shock protein; Energy metabolism; Immunity
期刊名称：ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH （ 影响因子：5.8； 五年影响因子：5.4 ）
ISSN： 0944-1344
年卷期： 2023 年
页码：
收录情况： SCI
摘要： During the dam discharging period, the strong aeration of high-speed water leads to the supersaturation of total dissolved gas (TDG) in the downstream water, which causes gas bubble disease (GBD) in fish and threatens their survival. TDG supersaturation has now become an ecological and environmental issue of global concern; however, the molecular mechanism underlying the physiological effect of TDG supersaturation on fish is poorly known. Here, we comprehensively investigated the effect of TDG supersaturation on Pelteobagrus fulvidraco at the histopathological, biochemical, transcriptomic, and metabolomic levels. After exposure to 116% TDG, P. fulvidraco exhibited classic GBD symptoms and pathological changes in gills. The level of superoxide dismutase was highly significantly decreased. Transcriptomic results revealed that heat shock proteins (HSPs) and a large number of genes involved in immunity were increased by TDG stress. A key environmental sensor PI3K/Akt/mTOR pathway was significantly stimulated for defence against stress. Integrated transcriptomic and metabolomic analyses revealed that key metabolites and genes were upregulated in the triacylglycerol synthesis pathway and that amino acid levels decreased, which might be associated with TDG supersaturation stress. The present study demonstrated that TDG supersaturation could cause severe physiological damage in fish. HSP genes, immune functions, and energy metabolic pathways were enhanced to counteract the adverse effects.
- 相关文献
作者其他论文 更多>>
-
Histological, ultrastructural, and multi-omic integration analysis on the response mechanisms of Acipenser dabryanus to hypoxia and reoxygenation
作者：Chen, Yeyu;Wu, Xiaoyun;Li, Pengcheng;Lai, Jiansheng;Ni, Luyun;Liu, Zhao;Song, Mingjiang;Li, Feiyang;Gong, Quan;Chen, Yeyu;Wu, Xiaoyun;Li, Pengcheng;Lai, Jiansheng;Ni, Luyun;Liu, Zhao;Song, Mingjiang;Li, Feiyang;Gong, Quan
关键词：Hypoxia; Reoxygenation; Acipenser dabryanus; Multi-omics
-
Cloning, Expression and Stability Analysis of Candidate Reference Genes in the Glacial Relict Hucho bleekeri Under Immune Stress
作者：Wu, Xiaoyun;Lai, Jiansheng;Chen, Yeyu;Yang, Huanchao;Chen, Yanling;Liu, Zhao;Tu, Quanyu;Yu, Yi;Li, Hua;Wu, Xiaoyun;Lai, Jiansheng;Chen, Yeyu;Yang, Huanchao;Chen, Yanling;Liu, Zhao;Tu, Quanyu;Yu, Yi;Li, Hua
关键词：qPCR; RefFinder; Salmonidae; tissue distribution
-
Underlying effect of TDG supersaturation on Hypophthalmichthys molitrix in the Dadu River
作者：Zhang, Yuanyi;Zhang, Qiyu;Wang, Fei;Shi, Haoran;Yang, Yao;Liu, Xiaoqing;Cai, Lu;Luo, Xiaohan;Chen, Yeyu
关键词：Total dissolved gas (TDG) supersaturation; Hypophthalmichthys molitrix; Energy metabolism; Immunity; Amino acid metabolism
-
Exploring the adsorption sites and mechanism of biochar towards tetracycline using machine learning
作者：Xian, Bo;Li, Qingzhi;Zhao, Huayi;Gong, Quan;Xian, Bo;Li, Qingzhi;Zhao, Huayi;Gong, Quan
关键词：Machine learning; Biochar; Tetracycline; Adsorption mechanism; Feature selection
-
The Pilot Study on the Histological and Ultrastructural Characteristics of Major Immune Organs (Spleen, Head Kidney, and Trunk Kidney) and Analysis of Pathological Features in Sichuan Taimen (Hucho bleekeri)
作者：Wei, Qinyao;Li, Hua;Chen, Yeyu;Liu, Zhao;Chen, Yanling;Yu, Yi;Tu, Quanyu;Liu, Guiliang;Du, Jun;Yang, Huanchao;Wei, Qinyao;Song, Zhaobin;Li, Hua;Chen, Yeyu;Liu, Zhao;Chen, Yanling;Yu, Yi;Tu, Quanyu;Liu, Guiliang;Du, Jun;Yang, Huanchao
关键词：head kidney; histology;
Hucho bleekeri -
Identification, Characterization, and Expression Analysis of CD79A and CD79B in the Sichuan Taimen (Hucho bleekeri)
作者：Chen, Yeyu;Yang, Huanchao;Wu, Xiaoyun;Liu, Zhao;Chen, Yanling;Wei, Qinyao;Lin, Jue;Yu, Yi;Tu, Quanyu;Li, Hua;Chen, Yeyu;Yang, Huanchao;Wu, Xiaoyun;Liu, Zhao;Chen, Yanling;Lin, Jue;Yu, Yi;Tu, Quanyu;Li, Hua;Wei, Qinyao
关键词：
-
The Effects of Dietary Supplementation with 25-Hydroxyvitamin D3 on the Antioxidant Capacity and Inflammatory Responses of Pelteobagrus fulvidraco
作者：Liu, Yi;Xie, Jiang;Shi, Qingchao;Qin, Chuanjie;Liu, Yi;Xie, Jiang;Shi, Qingchao;Qin, Chuanjie;Liu, Yi;Xie, Jiang;Shi, Qingchao;Qin, Chuanjie;Gong, Quan
关键词：metabolome; transcriptome; yellow catfish; 25(OH)D3; antioxidant; inflammatory
