Unlocking the therapeutic treasure of pomegranate leaf: A comprehensive review on phytochemical compounds, health benefits, and future prospects
文献类型： 外文期刊
作者： Yu, Manyou 1 ; Gouvinhas, Irene 2 ; Chen, Jian 1 ; Zhu, Yongqing 1 ; Deng, Junlin 1 ; Xiang, Zhuoya 1 ; Oliveira, Paula 2 ; Xia, Chen 1 ; Barros, Ana 2 ;
作者机构： 1.Sichuan Acad Agr Sci, Inst Agroprod Proc Sci & Technol, Inst Food Nutr & Hlth, Chengdu 610066, Peoples R China
2.Univ Tras os Montes & Alto Douro UTAD, Inov4Agro Inst Innovat Capac Bldg & Sustainabil Ag, Ctr Res & Technol Agroenvironm & Biol Sci CITAB, P-5000801 Vila Real, Portugal
3.UTAD, Sch Agr & Vet Sci, Dept Vet Sci, P-5000801 Vila Real, Portugal
4.UTAD, Sch Agr & Vet Sci, Dept Agron, P-5000801 Vila Real, Portugal
关键词： Punica granatum leaf; Bioactive compounds; Health-promoting effects; Antioxidant properties; Clinical applications
期刊名称：FOOD CHEMISTRY-X （ 影响因子：6.5； 五年影响因子：6.4 ）
ISSN： 2590-1575
年卷期： 2024 年 23 卷
页码：
收录情况： SCI
摘要： The exploration of sustainable and valuable by-products from industrial and agricultural processes is increasingly recognized for its economic, environmental and health advantages. This review examines the phytochemical constituents, biological properties, current applications and future directions of pomegranate ( Punica granatum L.) leaf (PGL). PGL exhibits broad biological activities, aiding in managing health conditions like chronic diseases, cancer, diabetes, obesity, and neurological disorders. Anti-cancer and anti-diabetic effects are demonstrated in vitro and in vivo using animal models. Anti-inflammatory and neuroprotective properties are also observed in cell cultures and animal studies. Its anti-microbial properties show efficacy against pathogens. However, variability in phytochemical composition due to different extraction methods and environmental conditions poses challenges for standardization. The review underscores the urgent need for comprehensive human clinical trials to confirm PGL 's therapeutic benefits and safety, calling for future research to fully harness PGL 's potential as a sustainable and bioactive compound in various industrial applications.
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