Synthesis of a dendritic estrogen cluster: A potential tool for studies of nuclear versus extranuclear pathways of estrogen actions
文献类型： 外文期刊
作者： Chen, Jian 1 ; Zheng, Hu 2 ; Song, Yan 1 ; Liang, Yu Feng 2 ; Qi, Qing Rong 2 ;
作者机构： 1.Sichuan Acad Agr Sci, Funct Food Drug Lab, Inst Agroprod Proc Sci & Technol, Chengdu 610066, Peoples R China
2.Sichuan Univ, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Dept Med Chem,W China Sch Pharm, Chengdu 610041, Peoples R China
关键词： Estrogen dendrimer;Synthesis;Nuclear and extranuclear;Receptor
期刊名称：CHINESE CHEMICAL LETTERS （ 影响因子：6.779； 五年影响因子：4.558 ）
ISSN： 1001-8417
年卷期： 2012 年 23 卷 12 期
页码：
收录情况： SCI
摘要： A novel estrogen dendrimer has been synthesized through a combination of divergent and convergent approaches in 9 practical steps and in good yields. It was characterized and confirmed by elemental analysis, FT-W, MS, H-1 NMR, C-13 NMR. The dendrimer contains 16 estrone units and is potentially a useful tool for the studies of estrogen actions. (C) 2012 Qing Rong Qi. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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