High Resolution Genome Wide Association Studies Reveal Rich Genetic Architectures of Grain Zinc and Iron in Common Wheat (Triticum aestivum L.)
文献类型： 外文期刊
作者： Tong, Jingyang 1 ; Zhao, Cong 1 ; Sun, Mengjing 1 ; Fu, Luping 1 ; Song, Jie 1 ; Liu, Dan 1 ; Zhang, Yelun 2 ; Zheng, Jianmin 3 ; Pu, Zongjun 3 ; Liu, Lianzheng 4 ; Rasheed, Awais 5 ; Li, Ming 1 ; Xia, Xianchun 1 ; He, Zhonghu 1 ; Hao, Yuanfeng 1 ;
作者机构： 1.Chinese Acad Agr Sci, Inst Crop Sci, Beijing, Peoples R China
2.Hebei Acad Agr & Forestry Sci, Inst Cereal & Oil Crops, Key Lab Crop Genet & Breeding Hebei Prov, Shijiazhuang, Peoples R China
3.Sichuan Acad Agr Sci, Crop Res Inst, Chengdu, Peoples R China
4.Xinjiang Acad Agr Sci, Res Inst Grain Crops, Urumqi, Peoples R China
5.Int Maizeand Wheat Improvement Ctr CIMMYT, China Off, Beijing, Peoples R China
6.Quaid I Azam Univ, Dept Plant Sci, Islamabad, Pakistan
关键词： biofortification; candidate genes; GWAS; iron; zinc
期刊名称：FRONTIERS IN PLANT SCIENCE （ 影响因子：6.627； 五年影响因子：7.255 ）
ISSN： 1664-462X
年卷期： 2022 年 13 卷
页码：
收录情况： SCI
摘要： Biofortification is a sustainable strategy to alleviate micronutrient deficiency in humans. It is necessary to improve grain zinc (GZnC) and iron concentrations (GFeC) in wheat based on genetic knowledge. However, the precise dissection of the genetic architecture underlying GZnC and GFeC remains challenging. In this study, high-resolution genome-wide association studies were conducted for GZnC and GFeC by three different models using 166 wheat cultivars and 373,106 polymorphic markers from the wheat 660K and 90K single nucleotide polymorphism (SNP) arrays. Totally, 25 and 16 stable loci were detected for GZnC and GFeC, respectively. Among them, 17 loci for GZnC and 8 for GFeC are likely to be new quantitative trait locus/loci (QTL). Based on gene annotations and expression profiles, 28 promising candidate genes were identified for Zn/Fe uptake (8), transport (11), storage (3), and regulations (6). Of them, 11 genes were putative wheat orthologs of known Arabidopsis and rice genes related to Zn/Fe homeostasis. A brief model, such as genes related to Zn/Fe homeostasis from root uptake, xylem transport to the final seed storage was proposed in wheat. Kompetitive allele-specific PCR (KASP) markers were successfully developed for two major QTL of GZnC on chromosome arms 3AL and 7AL, respectively, which were independent of thousand kernel weight and plant height. The 3AL QTL was further validated in a bi-parental population under multi-environments. A wheat multidrug and toxic compound extrusion (MATE) transporter TraesCS3A01G499300, the ortholog of rice gene OsPEZ2, was identified as a potential candidate gene. This study has advanced our knowledge of the genetic basis underlying GZnC and GFeC in wheat and provides valuable markers and candidate genes for wheat biofortification.
- 相关文献
作者其他论文 更多>>
-
The Importance of Molecular Structure for Textural and Physicochemical Properties of Extruded Wheat Flour
作者：Chai, Yuan;Li, Ming;Chai, Yuan;Zhang, Bo;Guo, Boli;Li, Ming;Wang, Ruibin;Tang, Yonglu;Li, Chaosu
关键词：extrusion expansion; degradation; molecular structure; temperature; specific mechanical energy
-
High-valent nickel oxyhydroxides self-derived through a low-temperature thermochemical strategy for an efficient oxygen evolution reaction
作者：Wang, Zhichao;Feng, Junjie;Wang, Jie;Deng, Jie;Deng, Jie;Qiu, Tiandong;Li, Chuncheng;He, Xiangyu;Zhu, Yachao;Chen, Si;Li, Ming;Hu, Dan;Huang, Wenli;Zhang, Yufeng;Yang, Guosheng
关键词：Oxygen evolution; NiFe electrocatalyst; Electronic structure; Water splitting
-
Fertilization regulates maize nutrient use efficiency through soil rhizosphere biological network and root transcriptome
作者：Hu, Huiling;Zhu, Bo;Yao, Zhiyuan;Luo, Bowen;Hu, Huiling;Gao, Shibin;Luo, Bowen;Hu, Huiling;Zhang, Xiao;Liu, Dan;Wu, Ling;Gao, Duojiang;Gao, Shiqiang;Gao, Shibin;Luo, Bowen;Hu, Huiling;Zhang, Xiao;Liu, Dan;Wu, Ling;Gao, Duojiang;Gao, Shiqiang;Gao, Shibin;Zheng, Hao;An, Ningxin;Guo, Jia;Nie, Zhi;Ma, Peng;Ma, Peng;Su, Shunzong
关键词：Fertilization strategies; Maize production; Soil biota; Trophic interactions; Root traits
-
Tailoring sodium storage with phosphorus-doped hollow carbon nanospheres: Atomic-level engineering of charge transport and ion dynamics
作者：Wang, Xilong;Zhang, Deng;Zheng, Qiaotian;Song, Jie;Chen, Dawei;Yan, Debing;He, Bin;Zhao, Qian;Tang, Mao;Xiao, Dan;Meng, Yan;Ying, Jing
关键词：Cassava starch; Phytic acid; Hollow nanosphere; Hard carbon; Sodium-ion batteries
-
Response of ZmPHO1 family members to low phosphorus stress and association of natural variation in ZmPHO1;2a reveal the role of low phosphorus tolerance
作者：Zhang, Haiying;Luo, Bowen;Luo, Xianfu;Li, Jing;Ma, Junchi;Wang, Wei;Zhao, Jin;Zhang, Xiao;Liu, Dan;Wu, Ling;Gao, Duojiang;Gao, Shiqiang;Gao, Shibin;Zhang, Haiying;Luo, Bowen;Luo, Xianfu;Li, Jing;Ma, Junchi;Wang, Wei;Zhao, Jin;Zhang, Xiao;Liu, Dan;Wu, Ling;Gao, Duojiang;Gao, Shiqiang;Gao, Shibin;Luo, Bowen;Gao, Shibin;Quan, Yucen;Zheng, Hao;Hu, Yaoyuan;Liu, Xinyue;Wang, Weixiu;Ma, Peng;Su, Shunzong
关键词：Candidate gene association analysis; Low-phosphorus stress; Maize; PHO1 family members; ZmPHO1; 2a
-
Multi-omics analysis reveals the physiological and molecular response to cold stress in different spring wheat cultivars at the booting stage
作者：Liu, Miao;Wu, Xiaoli;Li, Ming;Li, Shizhao;Xiong, Tao;Li, Chaosu;Tang, Yonglu;Liu, Miao;Li, Chaosu;Tang, Yonglu;Wu, Xiaoli
关键词：wheat; cold stress; physiological indicators; transcriptome; proteome; metabolome
-
Refining polyploid breeding in sweet potato through allele dosage enhancement
作者：Zhang, Xiangbo;Tang, Chaochen;Jiang, Bingzhi;Zhang, Rong;Yao, Zhufang;Huang, Lifei;Luo, Zhongxia;Zou, Hongda;Yang, Yiling;Wang, Zhangying;Li, Ming;Li, Ming;Wu, Yaoyao;Wu, Minyi;Chen, Ao;Hou, Xingliang;Liu, Xu;Wu, Minyi;Chen, Ao;Hou, Xingliang;Liu, Xu;Wu, Shan;Fei, Zhangjun;Fei, Zhangjun;Fu, Junjie
关键词：
