Multifunctional applications of silk fibroin in biomedical engineering: A comprehensive review on innovations and impact
文献类型： 外文期刊
作者： Lin, Yinglan 1 ; Zhao, Lifen 3 ; Jin, Hairong 1 ; Gu, Qiancheng 1 ; Lei, Lanjie 1 ; Fang, Chunyan 4 ; Pan, Xiaoyi 3 ;
作者机构： 1.Zhejiang Shuren Univ, Inst Translat Med, Key Lab Artificial Organs & Computat Med Zhejiang, Hangzhou 310015, Peoples R China
2.Ningxia Med Univ, Yinchuan 750004, Peoples R China
3.Wenzhou Med Univ, Affiliated Hosp 3, Wenzhou 325200, Peoples R China
4.Sichuan Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Chengdu 610066, Peoples R China
关键词： Silk fibroin; Biomedical engineering; Gels; Membranes; Microspheres
期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：8.5； 五年影响因子：8.7 ）
ISSN： 0141-8130
年卷期： 2025 年 309 卷
页码：
收录情况： SCI
摘要： Silk fibroin (SF) is a biomaterial naturally produced by certain insects (notably silkworms), animals such as spiders, or through recombinant methods in genetically modified organisms. Its exceptional mechanical properties, biocompatibility, degradability, and bioactivity have inspired extensive research. In biomedicine, SF has been utilized in various forms, including gels, membranes, microspheres, and more. It also demonstrates versatility for applications across medical devices, regenerative medicine, tissue engineering, and related fields. This review explores the current research status, advantages, limitations, and potential application pathways of SF in biomedical engineering. The objective is to stimulate innovative ideas and perspectives for research and applications involving silk.
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