文献类型： 外文期刊

作者： Huang, Lulin ² ; Cheng, Tingcai ¹ ; Xu, Pingzhen ¹ ; Fang, Ting ¹ ; Xia, Qingyou ¹ ;

作者机构： 1.Southwest Univ, State Key Lab Silkworm Genome Biol, Chongqing 400716, Peoples R China

2.Chongqing Univ, Inst Agron & Life Sci, Chongqing 400030, Peoples R China; Sichuan Acad Agr Sci, Inst Econ Crops Breeding & Cultivat, Chengdu 61000, Peoples R China

关键词： bacterial injection;developmental stages;multiple tissues;oral infection;pathogens;sexual dimorphism;silkworm;transcription factors

期刊名称：JOURNAL OF INSECT SCIENCE （ 影响因子：1.857； 五年影响因子：1.904 ）

ISSN： 1536-2442

年卷期： 2012 年 12 卷

页码：

收录情况： SCI

摘要： Transcription factors are present in all living organisms, and play vital roles in a wide range of biological processes. Studies of transcription factors will help reveal the complex regulation mechanism of organisms. So far, hundreds of domains have been identified that show transcription factor activity. Here, 281 reported transcription factor domains were used as seeds to search the transcription factors in genomes of Bombyx mori L. (Lepidoptera: Bombycidae) and four other model insects. Overall, 666 transcription factors including 36 basal factors and 630 other factors were identified in B. mori genome, which accounted for 4.56% of its genome. The silkworm transcription factors' expression profiles were investigated in relation to multiple tissues, developmental stages, sexual dimorphism, and responses to oral infection by pathogens and direct bacterial injection. These all provided rich clues for revealing the transcriptional regulation mechanism of silkworm organ differentiation, growth and development, sexual dimorphism, and response to pathogen infection.