您好，欢迎访问四川省农业科学院 机构知识库！

LML1, Encoding a Conserved Eukaryotic Release Factor 1 Protein, Regulates Cell Death and Pathogen Resistance by Forming a Conserved Complex with SPL33 in Rice

文献类型： 外文期刊

作者： Qin, Peng 2 ; Fan, Shijun 1 ; Deng, Luchang 1 ; Zhong, Guangrong 3 ; Zhang, Siwei 1 ; Li, Meng 1 ; Chen, Weilan 1 ; Wang, 1 ;

作者机构： 1.Sichuan Agr Univ, Rice Res Inst, Chengdu Wenjiang 611130, Sichuan, Peoples R China

2.Sichuan Agr Univ, State Key Lab Hybrid Rice, Chengdu Wenjiang 611130, Sichuan, Peoples R China

3.Neijiang Acad Agr, Hybrid Rice Res Ctr, Neijiang 641000, Sichuan, Peoples R China

4.Sichuan Acad Agr Sci, Crop Res Inst, Chengdu 610066, Sichuan, Peoples R China

关键词： Cell death; Eukaryotic elongation factor 1 alpha; Eukaryotic release factor 1; Lesion mimic; Pathogen resistance; Rice

期刊名称：PLANT AND CELL PHYSIOLOGY （ 影响因子：4.927； 五年影响因子：5.516 ）

ISSN： 0032-0781

年卷期： 2018 年 59 卷 5 期

页码：

收录情况： SCI

摘要： Lesion mimic mutants are powerful tools for unveiling the molecular connections between cell death and pathogen resistance. Various proteins responsible for lesion mimics have been identified; however, the mechanisms underlying lesion formation and pathogen resistance are still unknown. Here, we identify a lesion mimic mutant in rice, lesion mimic leaf 1 (lml1). The lml1 mutant exhibited abnormal cell death and resistance to both bacterial blight and rice blast. LML1 is expressed in all types of leaf cells, and encodes a novel eukaryotic release factor 1 (eRF1) protein located in the endoplasmic reticulum. Protein sequences of LML1 orthologs are conserved in yeast, animals and plants. LML1 can partially rescue the growth delay phenotype of the LML1 yeast ortholog mutant, dom34. Both /mil and mutants of AtLML1 (the LML1 Arabidopsis ortholog) exhibited a growth delay phenotype like dom34. This indicates that LML1 and its orthologs are functionally conserved. LML1 forms a functional complex with a eukaryotic elongation factor 1A (eEF1A)-like protein, SPL33/LMM5.1, whose mutant phenotype was similar to the lml1 phenotype. This complex was conserved between rice and yeast. Our work provides new insight into understanding the mechanism of cell death and pathogen resistance, and also lays a good foundation for studying the fundamental molecular function of Pelota/DOM34 and its orthologs in plants.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：四川省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台