文献类型： 外文期刊
作者： Qi, Jinwen 1 ; Zhang, Xin 2 ; Li, Ya 2 ; Xu, Shaoqi 2 ; Wang, Mei 2 ; Chen, Hu 2 ; Tang, Ni 2 ; Wang, Shuyao 2 ; Wang, Bin 2 ;
作者机构： 1.Sichuan Acad Agr Sci, Fisheries Inst, 156 Gaozhuang Bridge Community, Yibin, Sichuan, Peoples R China
2.Sichuan Agr Univ, Coll Anim Sci & Technol, Dept Aquaculture, 211 Huimin Rd, Chengdu, Sichuan, Peoples R China
3.Ocean Univ China, Fisheries Coll, Key Lab Mariculture, Minist Educ, 5 Yushan Rd, Qingdao, Shandong, Peoples R China
关键词： CRF; UCNs; CRF receptors; CRF-BP; Food intake; Feeding mechanisms
期刊名称：GENE （ 影响因子：3.688； 五年影响因子：3.329 ）
ISSN： 0378-1119
年卷期： 2020 年 733 卷
页码：
收录情况： SCI
摘要： CRF system is comprised of 4 homologous lineages, 2 main receptors (CRF-R1 and CRF-R2), and a binding protein CRF-BP. The homologous lineages are corticotropin-releasing factor (CRF), urotensin I (UI)/sauvagine (SVG)/urocortin 1 (UCN1), urocortin 2 (UCN2), and urocortin 3 (UCN3), and UI, SVG, UCN1 are orthologous genes. CRF system genes are widely distributed in the brain and gastrointestinal tract, which may relate to feeding regulation. According the research progress about CRF system on mammals and non-mammals, this paper summarized the discovery, structure, tissue distribution, appetite regulation and mechanism of CRF system in animals, which can provide the reference for further research and production of feeding regulation and growth in mammals and fish species.
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