Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity

Liu, Miaomiao; Zhang, Jingyu; Han, Jianying; Dai, Huanqin; Zhang, Lixin; Liu, Xueting; Li, Xiaolin; Zhang, Xiaoping; Abdel-Mageed, Wael M.; Abdel-Mageed, Wael M.; Li, Li; Li, Li; Wang, Wenzhao; Liu, Hung-wen; Liu, Hung-wen; Luo, Houwei; Han, Jianying; Quinn, Ronald J.; SCI

机构： Chinese Acad Sci, Inst Microbiol, Key Lab Pathogen Microbiol & Immunol, Beijing 100101, Peoples R China; Sichuan Acad Agr Sci, Soil & Fertilizer Res Inst, Chengdu 610066, Peoples R China; Sichuan Agr Univ, Dept Microbiol, Coll Resource & Environm, Chengdu 611130, Peoples R China; King Saud Univ, Dept Pharmacognosy, Coll Pharm, Riyadh 11451, Saudi Arabia; Assiut Univ, Dept Pharmacognosy, Fac ;

关键词： Biotransformation [4+2] cycloaddition reaction Tanshinone IIA Hypocrea sp